MOTS-C

This product is in research for the following:

MOTS-c (Mitochondrial ORF of the 12S ribosomal RNA type-c) is a 16-amino-acid peptide encoded directly by the mitochondrial genome. Often called an "exercise-mimetic," it plays a vital role in regulating cellular energy, boosting metabolism, improving insulin sensitivity, and promoting longevity. 

How It Works

• Energy Regulator: MOTS-c acts as a bridge between the mitochondria and the cell nucleus. Under metabolic stress or physical activity, it relocates to the nucleus and activates the AMPK pathway.

• Metabolic Flexibility: It helps the body efficiently shift between burning carbohydrates and fats, preventing diet-induced obesity and protecting against insulin resistance. [1, 2, 3]

Key Benefits

• Enhanced Physical Performance: Research in mice shows it can significantly increase physical capacity and healthspan.

• Metabolic Support: It improves glucose uptake in skeletal muscles and helps manage blood sugar levels.

• Anti-Aging: Natural endogenous levels of MOTS-c decline as we age. Supplementation is being heavily studied in longevity research for its potential rejuvenating effects on cellular health.